Nina Guérin

I focus my research on understanding micro-organisms at global scale using a two approaches based on -omics data analysis and wet lab experiments. After highschool, I graduated from interdisciplinary scientific bachelor « Frontiers of Life » at the University of Paris Cité. I then studied environmental microbiology during my master studies at the French National Museum of Natural History. I started my PhD at the LAGE in October 2020 under the supervision of Patrick Wincker and Quentin Carradec. I focus my research on the acclimation of photosynthetic picoeukaryote Pelagomonas calceolata through analysis of metagenomic and metatranscriptomic data on one hand, and culture in various controlled conditions followed by RNA-sequencing one the other hand.

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Thesis project : Acclimation of the picoeukaryote Pelagomonas to environmental changes

Photosynthetics picoeukaryotes (PPE) are abundant in all oceans and represent a major part of phytoplankton biomass and primary production. Climatic models predict an increase of oligotrophic areas in the next decades that could highly impact abundance and ecological role of PPE. Among them, micro-algae Pelagomonas calceolata (Stramenopiles/Pelagophyceae) is highly spread in all ocean but its ecological function is unknown. The aim of my PhD project is to understand how P. calceolata adapt to a wide range of environmental conditions. My goal is to study the transcriptomic activity of P. calceolata in Tara Oceans and Tara Pacific metatranscriptomics data thanks to the sequenced and assembled genome.  Simultaneously, P. calceolata will be cultivated under variable conditions in order to study its growth capacities according to specific environmental conditions such as temperature, iron availability, nitrogen source or nitrogen quantity. RNA will be extracted and sequenced in order to determine the genes involved in acclimatation. This double bio-informatic and wet laboratory method will allow to study expression of genes and functions involved in P. calceolata acclimatation and to understand how this cosmopolitan micro-algae can adapt to a wide range of environment.

Thesis supervisors : Quentin Carradec and Patrick Wincker

Pelagomonas calceolata, light microscopy


2020-now:PhD student (Genoscope, Laboratory of genomic analysis of eukaryotes)
Project: Acclimation of the photosynthetic picoeukaryote Pelagomonas calceolata to environmental changes.
Thesis director:  Dr. Wincker Patrick
2018-2020:Master degree ("Mechanisms of life and environment", French National Museum of Natural History, France)
Courses : Environemental microbiology, ecotoxicology, protistology.
2015-2018:Bachelor degree ("Frontiers of Life", University of Paris Cité, France)
Courses : biology, bioinformatics, physics, chemistry.